Method explainer · 4 min read

What Is Phenotypic Age?

An introduction to the blood-based model and what its result can—and cannot—mean.

AI-assisted editorial draft · Source check: 6 September 2026 · Independent reviewer: not yet assigned

A composite of routine measurements

Phenotypic Age combines chronological age and nine blood biomarkers. Its development used mortality-related information to create an interpretable age-scale composite.

Source 1: Aging / Levine et al.

It is not DNAm PhenoAge

The blood-based calculation and the DNA-methylation model share related terminology but require different inputs. Read the full method name on the product page and sample report.

Source 1: Aging / Levine et al.

Before using a calculator

Check the units, the complete marker list, how missing values are handled and whether processing happens locally or on a server. A mathematically correct result can still be misinterpreted. The original studies describe population associations, not an individual diagnosis.

Source 1: PLOS Medicine / Liu et al.
Educational information, not medical advice. This guide is an AI-assisted editorial draft awaiting independent review.
Check the original

Sources & verification

  1. An epigenetic biomarker of aging for lifespan and healthspan (2018)

    Aging / Levine et al. · Accessed 2026-09-06

  2. A new aging measure captures morbidity and mortality risk (2018)

    PLOS Medicine / Liu et al. · Accessed 2026-09-06