Phenotypic Age / PhenoAge
A published model built from routine blood chemistry and chronological age.
AI-assisted editorial draft · Source check: 6 September 2026 · Independent reviewer: not yet assigned
What it measures
A blood-based composite expressed in years. Phenotypic Age is distinct from DNAm PhenoAge, a methylation model trained to estimate a related target.
Source 1: Aging / Levine et al.Required inputs
Chronological age plus nine blood markers: albumin, creatinine, glucose, CRP, lymphocyte percentage, mean cell volume, red cell distribution width, alkaline phosphatase and white blood cell count.
How it was developed
Levine and colleagues selected clinical variables using mortality data, then translated the composite into an age scale.
Source 1: Aging / Levine et al.Outcome associations
The cited studies report associations with mortality and morbidity in population samples. Association does not tell an individual how long they will live.
Source 1: Aging / Levine et al.Limitations
Laboratory units, illness and collection conditions matter. A lower result is not proof of a longer life. Grade B is provisional pending a complete independent-replication review.
Can you calculate it yourself?
Possible using the published model, all required measurements and exact units. This directory does not collect lab results or perform the calculation.
Commercial use
A generic PhenoAge calculator is listed. InsideTracker InnerAge is a different, proprietary model.
Source 1: Aging / Levine et al.Source 2: PLOS Medicine / Liu et al.Sources & verification
- An epigenetic biomarker of aging for lifespan and healthspan (2018)
Aging / Levine et al. · Accessed 2026-09-06
- A new aging measure captures morbidity and mortality risk (2018)
PLOS Medicine / Liu et al. · Accessed 2026-09-06